Esr1 ELISA Kit for Mouse(Mus musculus) | EIAab.comEsr1 ELISA Kit for Mouse(Mus musculus)

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Esr1 (Gene name),

Estrogen receptor (Protein name ), ESR1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Esr1(Esr;Estr;Estra;Nr3a1);

Protein name:

Estrogen receptor(ER);

Alternative:

Estradiol receptor;ER-alpha;Nuclear receptor subfamily 3 group A member 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds DNA as a homodimer (By similarity). Can form a heterodimer with ESR2 (By similarity). Interacts with coactivator NCOA5. Interacts with NCOA7; the interaction is ligand-inducible. Interacts with AKAP13, CUEDC2, HEXIM1, KDM5A, MAP1S, PELP1, SMARD1, and UBE1C. Interacts with MUC1; the interaction is stimulated by 7 beta-estradiol (E2) and enhances ERS1-mediated transcription. Interacts with DNTTIP2, and UIMC1. Interacts with MLL2. Interacts with ATAD2; the interaction is enhanced by estradiol. Interacts with KIF18A and LDB1. Interacts with RLIM (via its C-terminus). Interacts with MACROD1. Interacts with SH2D4A and PLCG. Interacts with SH2D4A; the interaction blocks binding to PLCG and inhibits estrogen-induced cell proliferation. Interacts with DYNLL1. Interacts with CCDC62; the interaction requires estradiol and appears to enhance the transcription of target genes. Interacts with NR2C1; the interaction prevents homodimerization of ESR1 and suppresses its transcriptional activity and cell growth. Interacts with DYX1C1. Interacts with PRMT2. Interacts with PI3KR1 or PIK3R2, SRC and PTK2. Interacts with RBFOX2. Interacts with EP300; the interaction is estrogen-dependent and enhanced by CITED1. Interacts with CITED1; the interaction is estrogen-dependent (By similarity). Interacts with FAM120B, FOXL2, PHB2 and SLC30A9. Interacts with coactivators NCOA3 and NCOA6. Interacts with STK3/MST2 only in the presence of SAV1 and vice-versa.

Function:

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Can activate the transcriptional activity of TFF1.

Subcellular Location:

Nucleus Cytoplasm

Protein Attributes:

Sequence length:

599

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

599:

HRLHAPASRM | GVPPEEPSQT | QLATTSSTSA | HSLQTYYIPP | EAEGFPNTI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P19785

UniGene:

Mm.463262

Pfam:

PF00104

Pfam:

PF12743

String:

P19785

KEGG:

mmu:13982

Uniprot:

P19785

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ELISA Kit for Mouse ER

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E1050h

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ELISA Kit for Mouse ER

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E1050r

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96T

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ELISA Kit for Mouse ER

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E1050m

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ELISA Kit for Mouse ER

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E1050c

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ELISA Kit for Mouse ER

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E1050p

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ELISA Kit for Mouse ER

Cat.:

E1050b

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96T

CLIA Kit for Mouse ER

Cat.:

U1050c

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96T

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CLIA Kit for Mouse ER

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U1050m

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96T

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CLIA Kit for Mouse ER

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U1050r

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96T

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CLIA Kit for Mouse ER

Cat.:

U1050h

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96T

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CLIA Kit for Mouse ER

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U1050b

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96T

CLIA Kit for Mouse ER

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U1050p

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96T

Polyclonal Antibody for Mouse ER

Cat.:

P1050Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse ER

Cat.:

P1050Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse ER

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P1050Rb-h

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Monoclonal Antibody for Mouse ER

Protein for Mouse ER

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Structural organization and expression of the mouse estrogen receptor."
White R. , Lees J.A. , Needham M. , Ham J. , Parker M.
Mol. Endocrinol.1:735-744(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Uterus.
2.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Bone.
tissue: Thymus.
3.

"Tissue-specific expression of multiple mRNA variants of the mouse estrogen receptor alpha gene."
Kos M. , O'Brien S. , Flouriot G. , Gannon F.
FEBS Lett.477:15-20(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-22
strain: C57BL/6J.
tissue: Liver.
4.

"Screening for candidate genes of mouse autoimmune diseases."
Ma R.Z. , Teuscher C.
Submitted (1999-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 269-599;VARIANT GLN-591
strain: B10.S/J.
strain: SJL/J.
tissue: Spleen.
5.

"Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor."
Cavailles V. , Dauvois S. , L'Horset F. , Lopez G. , Hoare S. , Kushner P.J. , Parker M.G.
EMBO J.14:3741-3751(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NRIP1
6.

"Molecular determinants of the estrogen receptor-coactivator interface."
Mak H.Y. , Hoare S. , Henttu P.M. , Parker M.G.
Mol. Cell. Biol.19:3895-3903(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH NCOA1;MUTAGENESIS OF ILE-362; LYS-366; LEU-376; VAL-380 AND LEU-543
7.

"Mutations in the estrogen receptor ligand binding domain discriminate between hormone-dependent transactivation and transrepression."
Valentine J.E. , Kalkhoven E. , White R. , Hoare S. , Parker M.G.
J. Biol. Chem.275:25322-25329(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH NCOA1;MUTAGENESIS OF PHE-371; LEU-508; ALA-509; LEU-512; LEU-515; GLY-525; ASP-542; 543-LEU-LEU-544; GLU-546; 547-MET-LEU-548 AND ASP-549
8.

"Constitutive coactivator of peroxisome proliferator-activated receptor (PPARgamma), a novel coactivator of PPARgamma that promotes adipogenesis."
Li D. , Kang Q. , Wang D.-M.
Mol. Endocrinol.21:2320-2333(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FAM120B
9.

"A subpopulation of estrogen receptors are modified by O-linked N-acetylglucosamine."
Jiang M.S. , Hart G.W.
J. Biol. Chem.272:2421-2428(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-575
10.

"Glycosylation of the murine estrogen receptor-alpha."
Cheng X. , Hart G.W.
J. Steroid Biochem. Mol. Biol.75:147-158(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT SER-10; THR-50 AND THR-575
11.

"The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function."
Torchia J. , Rose D.W. , Inostroza J. , Kamei Y. , Westin S. , Glass C.K. , Rosenfeld M.G.
Nature387:677-684(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCOA3
12.

"Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR."
Zhu Y.-J. , Kan L. , Qi C. , Kanwar Y.S. , Yeldandi A.V. , Rao M.S. , Reddy J.K.
J. Biol. Chem.275:13510-13516(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCOA6
13.

"Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases."
Kurtev V. , Margueron R. , Kroboth K. , Ogris E. , Cavailles V. , Seiser C.
J. Biol. Chem.279:24834-24843(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PHB2
14.

"GAC63, a GRIP1-dependent nuclear receptor coactivator."
Chen Y.-H. , Kim J.H. , Stallcup M.R.
Mol. Cell. Biol.25:5965-5972(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SLC30A9
15.

"Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation."
Uhlenhaut N.H. , Jakob S. , Anlag K. , Eisenberger T. , Sekido R. , Kress J. , Treier A.C. , Klugmann C. , Klasen C. , Holter N.I. , Riethmacher D. , Schutz G. , Cooney A.J. , Lovell-Badge R. , Treier M.
Cell139:1130-1142(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FOXL2
16.

"DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors."
Pedram A. , Razandi M. , Deschenes R.J. , Levin E.R.
Mol. Biol. Cell23:188-199(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-451;MUTAGENESIS OF CYS-451

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